About 1 result found for searched term "Trimetrexate trihydrochloride" (0.128 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28781 | Trimetrexate trihydrochloride | Dihydrofolate reductase |
| CI-898 trihydrochloride | ||
| Trimetrexate (CI-898) trihydrochloride is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. | ||
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